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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
10.3
Human Site:
Y1192
Identified Species:
18.89
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
Y1192
A
Q
K
L
N
E
N
Y
E
E
V
K
S
I
T
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
Y1192
A
Q
K
L
N
E
N
Y
E
E
V
K
S
I
T
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
Y1192
A
Q
K
L
N
E
N
Y
E
E
M
K
S
I
T
Dog
Lupus familis
XP_852631
1216
141588
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
Q1142
Q
Q
Q
L
L
S
T
Q
E
A
M
S
K
L
Q
Rat
Rattus norvegicus
Q7TSP2
1385
159522
T57
C
L
S
V
L
S
Q
T
A
L
R
L
H
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
Q822
L
K
Y
I
N
S
N
Q
E
Y
V
A
L
K
Q
Frog
Xenopus laevis
NP_001080954
2954
339950
E1382
T
K
K
L
N
G
L
E
K
E
I
L
G
K
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
L685
K
C
E
E
L
E
K
L
I
A
D
L
E
S
K
Honey Bee
Apis mellifera
XP_001121311
1418
164919
L90
M
M
G
G
T
E
E
L
G
I
I
P
L
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
D1137
Q
E
I
M
K
Q
K
D
K
D
L
R
D
I
E
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
T20
L
S
S
E
D
A
K
T
S
P
W
K
I
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
93.3
0
N.A.
20
0
N.A.
N.A.
26.6
26.6
N.A.
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
0
N.A.
40
6.6
N.A.
N.A.
40
53.3
N.A.
N.A.
13.3
13.3
N.A.
53.3
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
0
0
8
0
0
8
16
0
8
0
8
0
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
8
8
0
8
0
0
% D
% Glu:
0
8
8
16
0
39
8
8
39
31
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
8
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
8
8
16
0
8
31
8
% I
% Lys:
8
16
31
0
8
0
24
0
16
0
0
31
8
16
8
% K
% Leu:
16
8
0
39
24
0
8
16
0
8
8
24
16
8
0
% L
% Met:
8
8
0
8
0
0
0
0
0
0
16
0
0
0
0
% M
% Asn:
0
0
0
0
39
0
31
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% P
% Gln:
16
31
8
0
0
8
8
16
0
0
0
0
0
0
16
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% R
% Ser:
0
8
16
0
0
24
0
0
8
0
0
8
24
24
16
% S
% Thr:
8
0
0
0
8
0
8
16
0
0
0
0
0
0
24
% T
% Val:
0
0
0
8
0
0
0
0
0
0
24
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
24
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _